The mycological research, conducted in the territory of the Republic of Moldova during 1976-2018, allowed inventorying 39 species of macromycetes of 5 genera (Boletus, Leccinum, Leccinellum, Phylloporus, Xerocomellus) in the family Boletaceae. The absolute majority of the species of Boletaceae in the studied area are mycorrhizal fungi, which form symbioses with the main forest-forming species of oak and beech. For each species in the annotated list, it has been presented: the scientific name, the biological form and the habitat, the phenophase of the spore-containing structures and the frequency, chorological data and information on the significance.