In the pharmacotherapy of patients with concomitant cardiovascular disease is important maintaining the continuity between the hospital and outpatient treatment. Pharmacoepidemiological study spent in hospitals in Kursk (Russia) and Chisinau (Moldova) has reported that during the pharmacotherapy of these patients were fulfilled the international and national recommendations for treatment of patients with coronary heart disease, arterial hypertension, chronic heart failure with the use of the modern drugs from groups of beta-blockers, calcium channel blockers, angiotensin converting enzyme inhibitors, angiotensin II receptor antagonists, nitrates, antiplatelets, statins, diuretics, myocardial cytoprotectors and there is adequate level of continuity between the hospital and outpatient stage of therapy in the both city: Kursk and Chisinau.