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547.915:54.04:615.451 (1) |
Органическая химия (484) |
Формы лекарственных средств. Медицинские материалы. Оборудование (100) |
SM ISO690:2012 WAN SALLEH , Wan Mohd Nuzul Hakimi, NADRI, Muhammad Helmi, KHAMIS, Shamsul. Chemical composition and lipoxygenase inhibitory activity of the essential oil of Alstonia angustiloba. In: Chemistry Journal of Moldova, 2021, nr. 2(16), pp. 112-116. ISSN 1857-1727. DOI: https://doi.org/10.19261/cjm.2021.848 |
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Chemistry Journal of Moldova | ||||||
Numărul 2(16) / 2021 / ISSN 1857-1727 /ISSNe 2345-1688 | ||||||
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DOI:https://doi.org/10.19261/cjm.2021.848 | ||||||
CZU: 547.915:54.04:615.451 | ||||||
Pag. 112-116 | ||||||
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This study was aimed to investigate the chemical compositions and lipoxygenase inhibitory activity of the essential oil extracted from Alstonia angustiloba growing in Malaysia. The essential oils were obtained by hydrodistillation and fully characterized by gas chromatography and gas chromatography-mass spectrometry methods. Analysis of the A. angustiloba essential oil resulted in the identification of twenty-five chemical components, which constitute 90.8% of the total oil. The most abundant components of A. angustiloba oil were linalool (21.2%), 1,8-cineole (16.8%), α-terpineol (9.5%), terpinen-4-ol (8.5%), β-caryophyllene (6.2%), and caryophyllene oxide (5.2%). The essential oil displayed moderate activity towards lipoxygenase inhibitory activity with an IC50 value of 45.8 μg/mL. |
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Cuvinte-cheie essential oil, hydrodistillation, lipoxygenase, Alstonia angustiloba, Apocynaceae |
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