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Ultima descărcare din IBN: 2023-09-29 08:29 |
Căutarea după subiecte similare conform CZU |
619:615.9:636.2 (1) |
Științe medicale. Medicină (11196) |
Toxicologie generală. Studii generale asupra otrăvurilor şi otrăvirii (intoxicaţiei) (45) |
Rumegătoare mari, taurine. Vite, boi (203) |
SM ISO690:2012 ГУТЫЙ, Б.. Влияние хлорида кадмия на уровень промежуточных и конечных продуктов
перекисного окисления липидов в крови бычков. In: Ştiinţa Agricolă, 2014, nr. 1, pp. 107-110. ISSN 1857-0003. |
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Ştiinţa Agricolă | ||||||
Numărul 1 / 2014 / ISSN 1857-0003 /ISSNe 2587-3202 | ||||||
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CZU: 619:615.9:636.2 | ||||||
Pag. 107-110 | ||||||
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Rezumat | ||||||
Based on numerous clinical and experimental investigations, the important role of lipid peroxidation (LP) in the development of many toxicoses has proved in recent years. Environmental cadmium pollution and its negative effect on animals, especially on young cattle, are the reasons why the problem of studying the
cadmium toxicosis pathogenesis in farm animals appears to be particularly topical. The aim of our research was to determine the effect of cadmium chloride in toxic doses of 0.02 and 0.03 mg/kg of body weight on the level of intermediate and end LP products in the blood of young cattle. Feeding cadmium chloride-supplemented diets to bull calves led to the increased concentrations of LP products: malonic dialdehyde (MDA) and dienic conjugates (DC). On the twenty-fourth day of the experiment the DC level was by 33%, and the MDA level – by 28% higher as compared to the control group. The identified changes of the MDA and DC levels in the blood serum of experimental
animals was probably due to the fact that the toxic effect of cadmium promotes changes in steady-state concentrations
of radical metabolites О2˙-, ˙ОН, НО2˙, which, in their turn, initiate LP processes. The concentration of radical
metabolites increased after feeding animals with cadmium chloride. Based on the research results, we can conclude
that the LP intensity changes when animals are fed with cadmium in different doses and it also depends on the length of time that has passed after the feeding. |
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Cuvinte-cheie Телята, Токсичность, Малоновый диальдегид, Хлорид кадмия, Перекисное окисление липидов |
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