Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
849 21 |
Ultima descărcare din IBN: 2021-12-15 16:21 |
Căutarea după subiecte similare conform CZU |
618.14-006.36:618.177-08 (1) |
Științe medicale. Medicină (11191) |
SM ISO690:2012 BURAC, Mihaela, FRIPTU, Valentin. Disfuncția endometrială la pacientele cu infertilitate primară. In: Buletin de Perinatologie, 2019, nr. 4(85), pp. 14-18. ISSN 1810-5289. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Buletin de Perinatologie | ||||||
Numărul 4(85) / 2019 / ISSN 1810-5289 | ||||||
|
||||||
CZU: 618.14-006.36:618.177-08 | ||||||
Pag. 14-18 | ||||||
|
||||||
Descarcă PDF | ||||||
Rezumat | ||||||
Introduction. Endometrial dysfunction represent the morpho-functional changes of the endometrium, which can be reversible or irreversible, grounded by molecular mechanisms disruptions, which subsequently lead to infertility, embryo implantation deficiency, placental insufficiency, or even embryo death. The aim of the study. Evaluation of clinical and morphological particularities of endometrial dysfunction in primary infertility patients. Material and methods. A prospective study was conducted, which included 96 patients divided into two groups. The study group (L1) included 48 primary infertility patients and control group (L0) – 48 fertile patients. In both groups, we performed the endometrial biopsy in the proliferative phase with the Pipelle endometrial aspiration curette. The study was approved by the Research Ethics Commission of the State University of Medicine and Pharmacy „Nicolae Testemitanu”, Chisinau, Republic of Moldova (No. 79/62 of 26.04.2017). The patients signed an informed consent to participate in the research. The statistical analysis was performed using SPSS 20 and Microsoft Excel 2016. Results. The mean age of the patients in the study group was 29,0 ± 4,58 and in the control group 29,2 ± 4,29 (p=0,801). În the study group the duration of infertility was mostly: 2 years – 20,8%, 3 years – 22,9% and more than 5 years – 27,1%. The most representative bacteria in the endometrium of the patients with primary infertility was Lactobacillus spp. 75%, c2 = 0,236; p = 0,627; followed by Ureaplasma urealiticum + parvum in 37,5%, c2 = 13,714; p 0,001; Atopobium vaginae – 25%, c2 = 1,640; p = 0,20; Enterobacteriaceae 18,8%, c2 = 9,931; p = 0,002 wich lead to inflammatory changes in the endometrium of primary infertility patients in 79,2%, c2 = 22,238; p <0,001. Conclusion. In our study we have demonstrated that the patients with primary infertility, more often compared with fertile patients suffer from gynecological pathologies, sexually transmitted diseases and also their endometrium is populated by a n |
||||||
Cuvinte-cheie endometrium, primary infertility, endometrial microbiome, microbiome in reproduction, эндометрий, первичное бесплодие, микробиом эндометрия, микробиом в репродукции |
||||||
|