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SM ISO690:2012 ЗЫКОВ, А., БАЧМАН, Е., МОГИЛЕВКИНА, И.. Диагностика преждевременного разрыва плодных оболочек. In: Buletin de Perinatologie, 2014, nr. 1(61), pp. 15-19. ISSN 1810-5289. |
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Buletin de Perinatologie | ||||||
Numărul 1(61) / 2014 / ISSN 1810-5289 | ||||||
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Pag. 15-19 | ||||||
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Objectіve. Calculation of predictive value, sensitivity and specificity of the diagnostic test ActimPROM for premature rupture of membranes detection. Material and methods. In prospective study 27 pregnant women between 24 and 41 gestational weeks who have been admitted to the Donetsk Regional Center for Maternal and Child Protection during June 1- August 1, 2011 with suspected premature rupture of the membranes (PROM) without uterine contractions were included. “Fern” test and ActimPROM have been used. The tests diagnostic capabilities were calculated in comparison to final clinical diagnosis of PROM. Both tests prognostic values were compared. Sensitivity, specificity and predictive value of the tests were evaluated by statistical package MedStat (Lyakh J.E., Gurianov V.G., 2004-2012) using logistic regression and constructing ROC - curve. p<0,05 was considered statistically significant.16 Results. On admission there was: in 21 cases suspected and in 6 – obvious leakage of water due to premature rupture of the membranes. Test ActimPROM has demonstrated sensitivity of 100% (95% CI, 82.4% -100%), specificity - 83.,3% (95% CI 35,9% -99,6%), the likelihood ratio LR = 6,0 (95% CI 1,0-35,9). The “fern” test sensitivity was 73,7% (95% CI 48,8% -90,9%), specificity - 33,3% (95% CI 4,3% -77,7%), the likelihood ratio LR = 1,1 (95% CI 0,6-2,1). -LR = 0,8 (95% CI 0,2-3,1). According to logistic regression analysis, the “fern” test is unsuitable for PROM detection. Conclusions. Use of ActimPROM test increases precision of premature rupture of the membranes diagnosis. Simplicity and speed in getting the test results let us to recommend its use in obstetric practice. We do not recommend use of the “fern” test in view of its low diagnostic properties. Objectіve. Calculation of predictive value, sensitivity and specificity of the diagnostic test ActimPROM for premature rupture of membranes detection. Material and methods. In prospective study 27 pregnant women between 24 and 41 gestational weeks who have been admitted to the Donetsk Regional Center for Maternal and Child Protection during June 1- August 1, 2011 with suspected premature rupture of the membranes (PROM) without uterine contractions were included. “Fern” test and ActimPROM have been used. The tests diagnostic capabilities were calculated in comparison to final clinical diagnosis of PROM. Both tests prognostic values were compared. Sensitivity, specificity and predictive value of the tests were evaluated by statistical package MedStat (Lyakh J.E., Gurianov V.G., 2004-2012) using logistic regression and constructing ROC - curve. p<0,05 was considered statistically significant. Results. On admission there was: in 21 cases suspected and in 6 – obvious leakage of water due to premature rupture of the membranes. Test ActimPROM has demonstrated sensitivity of 100% (95% CI, 82.4% -100%), specificity - 83.,3% (95% CI 35,9% -99,6%), the likelihood ratio LR = 6,0 (95% CI 1,0-35,9). The “fern” test sensitivity was 73,7% (95% CI 48,8% -90,9%), specificity - 33,3% (95% CI 4,3% -77,7%), the likelihood ratio LR = 1,1 (95% CI 0,6-2,1). -LR = 0,8 (95% CI 0,2-3,1). According to logistic regression analysis, the “fern” test is unsuitable for PROM detection. Conclusions. Use of ActimPROM test increases precision of premature rupture of the membranes diagnosis. Simplicity and speed in getting the test results let us to recommend its use in obstetric practice. We do not recommend use of the “fern” test in view of its low diagnostic properties. |
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Cuvinte-cheie pregnancy, sensitivity and specificity, premature rupture of the membranes, “fern” test, protein-1, insulin-like growth factor binding. |
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