Introduction. Deep endometriosis (DE) has the widest spectrum of localizations, the most pronounced clinic, it mimics many diseases, is the most often missed in the diagnostic process, it undergoes rarely drug treatment, progresses during pregnancy, unlike other forms of endometriosis (E). The ENZIAN score for DE, used in this study, brings diagnostic criteria in addition to previous classifications, specifying the compartment of the lesion based on the «4D» clinic. Material and methods. A case-control study was carried out on 141 patients hospitalized in IMSP SCM NR.1, with the diagnosis of E confirmed laparoscopically, divided into 2 groups: DE and other forms of E. Results. The use of the ENZIAN classification during laparoscopy in the group of patients revealed a 54.61% incidence of DE. The study demonstrated the statistically true correlation between dyspareunia and compartment B by ENZIAN (p < 0.001), dyschezia and comp. A and C (p < 0.001), associated with rectal tenesmus in 33.76%, defecation disorders in 37.66%, dysmenorrhea and comp. FA (p < 0.001), associated with menorrhagia in 25.97%, dysuria and comp. FB (p < 0.001), associated with bladder tenesmus in 18.2% and hematuria in 9.09% compared to the control group where the basic symptom was infertility and moderate dysmenorrhea, associated with cystic formations on the ovaries. Conclusions. However, the symptoms presented by patients in DE may indicate the compartment of the affection after ENZIAN, thus requiring multidisciplinary diagnosis and approach.