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SM ISO690:2012 ANDRONACHE, Lilia. Influenţa compuşilor coordinativi ai cuprului
şi a combinaţiei lor cu remediul ianobacterian bior asupra enzimelor antioxidante în rinichi
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2012, nr. 1(13), pp. 130-134. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(13) / 2012 / ISSN 1857-1719 | ||||||
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Pag. 130-134 | ||||||
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Influence of copper coordination compounds and their combinations with cyanobacterial remedy bior on the activity of antioxidant enzymes in the kindey
The influence of copper coordination compounds CMT-28, CMT-67 and their combinations with the cyanobacterial remedy BioR on kidney antioxidant enzymes activity in rats with carbon tetrachloride poisoning. In subacute intoxication with CCl4 BioR induced the increase in superoxide dismutase, catalase and glutathione peroxidase activities in the renal tissue, which protects kidney cells and subcellular structures by neutralizing thre excess of free radicals of oxygen, oxygen hydroperoxide and other peroxides. Compound CMT-28 induces superoxide dismutase activity, while CMT-67 complex causes a significant increase in the activities of SOD, GPO and GST in kidney tissue of laboratory animals with subacute CCl4 intoxication. BioR remedy shows synergistic action with CMT-28 and CMT-67, which was caracterised by the maintainance of high activity of the investigated antioxidant enzymes. |
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