Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
281 12 |
Ultima descărcare din IBN: 2024-01-28 15:06 |
Căutarea după subiecte similare conform CZU |
616-002.77-036 (2) |
Patologie. Medicină clinică (6996) |
SM ISO690:2012 NISTOR, Alesea. Assessment of inflammatory status in patients with seronegative rheumatoid arthritis. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 207. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616-002.77-036 | ||||||
Pag. 207-207 | ||||||
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Rezumat | ||||||
Introduction. Rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by serious damage of the joints. Traditionally, serological status has been used to classify 2 subgroups of patients within RA- seronegative or seropositive - to distinguish the progression of the disease and the response to treatment. Objective of the study. To research of the status of RA activity depending on the presence of rheumatoid factor and anti-CCP antibodies. Material and methods. 92 patients with RA were identified according to the criteria of the American College of Rheumatology (ACR), who were hospitalized in the clinic Discipline of rheumatology and nephrology of Nicolae Testemitanu University between 2011 and 2021. Results. Appreciating the activity of the disease at baseline, 28 TJC (4.7 ± 2.9 vs. 3.3 ± 2.7, p = 0.004), 28 SJC (4.3 ± 3.0 vs. 2.9 ± 2.3, p = 0.001) and DAS28-ESR (5.1 ± 1.0 vs. 4.7 ± 1.0, p = 0.043) were significantly higher in SNRA patients compared to SPRA. This finding became more visible when these values were compared between SNRA patients who meet the 2010 ACR/EULAR criteria and patients with SPRA. Conclusion. Patients with SNRA have a more active disease and similar radiographic lesions at presentation compared to patients with SPRA. Although patients with SNRA have shown a better response to treatment, doctors should be aware of the considerable clinical burden of SNRA, especially at the onset of the disease. |
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Cuvinte-cheie rheumatoid arthritis, seronegative, inflammatory activity, artrita reumatoidă, seronegativă, activitate inflamatorie |
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