Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
243 11 |
Ultima descărcare din IBN: 2024-03-11 09:24 |
Căutarea după subiecte similare conform CZU |
616.12-009.72-085 (1) |
Patologia sistemului circulator, a vaselor sanguine. Tulburări cardiovasculare (978) |
SM ISO690:2012 CHETRUŞ, Olga. The importance of cytoprotective treatment in patients with angina pectoris. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 196. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.12-009.72-085 | ||||||
Pag. 196-196 | ||||||
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Introduction: cardiovascular system diseases occupy in most countries of the world the first place among the causes of deaths. The epidemiological situation in the Republic of Moldova is characterized by the term „supermortality” due to cardiovascular diseases. Objective of the study. To investigate the effectiveness of the pharmacotherapy of ischemic heart disease by metabolic approaches - meldonium. Material and methods. An open randomized clinical trial was conducted that included 160 patients with ischemic heart disease (117 men and 43 women) aged 37 to 81 years. Of them, 142 patients with angina pectoris of stable effort from different functional classes and 21 – unstable. Results. The additional indication of meldonium on the ECG showed an improvement in the repolarization phase in the form of reducing the depth of the negative wave “T” from 1.5 mm to 0.2 mm (p < 0.05) and the decrease in the number of negative wave derivatives “T” from 2.6 to 0.4 (p = 0.07). At the end of the observation period, patients treated with meldonium showed improvement in the exercise test, increasing the result from 310.66 ± 24.74 meters to 476.50 ± 43.5 meters (p < 0.05). Conclusions. The inclusion of metabolic drugs in the complex treatment of patients with stable angina increases the clinical effectiveness of basic pharmacotherapy 4 times when prescribing meldonium (59.16% compared to basic therapy 15.95%, p < 0.001). |
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Cuvinte-cheie cardioprotection, angina pectoris, meldonium, cardioprotecție, angina pectorală, meldonium |
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